Day: April 13, 2022

COA of Formula: C30H21P. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: Tri(naphthalen-1-yl)phosphine, is researched, Molecular C30H21P, CAS is 3411-48-1, about Tri(1-naphthyl)phosphine as a ligand in palladium-free Sonogashira cross-coupling of arylhalogenides with acetylenes. Author is Govdi, Anastasiya I.; Vasilevsky, Sergey F.; Malysheva, Svetlana F.; Kazheva, Olga N.; Dyachenko, Oleg A.; Kuimov, Vladimir A..

Tri(1-naphthyl)phosphine (Np3P) was easily prepared in 34% yield from red phosphorus and 1-bromonaphthalene in superbasic system t-BuONa/DMSO. The expedient procedure for the synthesis of diaryl acetylenes ArC≡CAr1 [Ar = Ph, 4-MeOC6H4, 2-O2NC6H4, etc.; Ar1 = Ph, 4-MeC6H4, 4-BrC6H4, etc.] by Sonogashira coupling of aryl iodides with terminal alkynes using Np3P as a ligand was developed. For the first time, it was found that the reaction with compounds containing electron-donating substituents preferably afforded buta-1,3-diynes ArC≡C-C≡CAr1.

In some applications, this compound(3411-48-1)COA of Formula: C30H21P is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

Bould, Jonathan; Tok, Oleg; Passarelli, Vincenzo; Londesborough, Michael G. S.; Macias, Ramon published an article about the compound: 1,2-Bis(diphenylphosphino)ethane( cas:1663-45-2,SMILESS:P(CCP(C1=CC=CC=C1)C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4 ).Synthetic Route of C26H24P2. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:1663-45-2) through the article.

The discovery of systems that interact with small mols. plays a vital facilitating role in the development of devices that show sensitivity to their surroundings and an ability to quickly relay chem. and phys. information. Herein, the authors report on the reaction of [NiCl2(dppe)] with decaborane that produces in usable yield a new 11-vertex nickelaborane, [7,7-(dppe)-nido-7-NiB10H12] (1), which shows interesting reactivity and functionality toward CO and ethylisonitrile. This contribution describes the synthesis and full structural characterization of 1 and its small-mol. EtNC and CO adducts, 2 and 3, and delineates the dynamic mol. behavior of all of these species in solution This information sets a foundation from which more advanced work on this and related metallaborane systems can be conceived and provides a more general reference to how NMR spectroscopy, combined with DFT calculations, can be used to analyze the precise locomotion of labile ligands around a metal center held within a borane cluster. The contra-rotation of the {L2M} moiety with respect to the face-bound borane fragment in [L2MB10H12] compounds, previously a curiosity chiefly restricted to NMR measurement, is now shown to control the elimination and uptake of ligands in [(L)(dppe)NiB10H12] (L = CO and EtNC).

In some applications, this compound(1663-45-2)Synthetic Route of C26H24P2 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

Application of 1663-45-2. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 1,2-Bis(diphenylphosphino)ethane, is researched, Molecular C26H24P2, CAS is 1663-45-2, about Highly Photoluminescent Blue Ionic Platinum-Based Emitters.

New cycloplatinated N-heterocyclic carbene (NHC) compounds with chelate diphosphines (P^P) as ancillary ligands: [Pt(R-C^C*)(P^P)]PF6 (R = H, P^P = dppm (1A), dppe (2A), dppbz (3A); R = CN, P^P = dppm (1B), dppe (2B), dppbz (3B)) have been prepared from the corresponding starting material [{Pt(R-C^C*)(μ-Cl)}2] (R = H, A, R = CN, B) and fully characterized. The new compound A has been prepared by a stepwise protocol. The photophys. properties of 1A-3A and 1B-3B have been widely studied and supported by the time-dependent-d. functional theory. These compounds show an efficient blue (dppe, dppbz) or cyan (dppm) emission in PMMA films (5 weight %), with photoluminescence quantum yield (PLQY) ranging from 30% to 87% under an argon atm. This emission has been assigned mainly to transitions from 3ILCT [π(NHC) → π*(NHC)] excited states with some 3LL’CT [π(NHC) → π*(P^P)] character. The electroluminescence of these materials in proof-of-concept solution-processed organic light-emitting diodes containing 3A and 3B as dopants was investigated. The CIE coordinates for devices based on 3A (0.22, 0.41) and 3B (0.24, 0.44) fit within the sky blue region. Highly photoluminescent ionic platinum-based emitters, [Pt(R-C^C*)(P^P)]PF6, were prepared They show an efficient blue or cyan emission in PMMA films (5 weight %), with PLQY ranging from 30% to 87%. Solution-processed organic light-emitting diodes based on 3A and 3B show CIE coordinates (0.22, 0.41 (3A); 0.24, 044 (3B)) fitting within the sky blue region.

In some applications, this compound(1663-45-2)Application of 1663-45-2 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

Reference of Tri(naphthalen-1-yl)phosphine. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: Tri(naphthalen-1-yl)phosphine, is researched, Molecular C30H21P, CAS is 3411-48-1, about Recyclable and reusable Pd(OAc)2/P(1-Nap)3/[bmim][PF6]/H2O system for the addition of arylboronic acids to aldehydes. Author is Zhao, Hong; Cheng, Mingzhu; Zhang, Tinli; Cai, Mingzhong.

A stable and efficient Pd(OAc)2/P(1-Nap)3[tri(1-naphthyl)phosphine] catalytic system for the addition of arylboronic acids to aldehydes was developed. In the presence of Pd(OAc)2 and P(1-Nap)3, the addition reaction of arylboronic acids with aldehydes was carried out smoothly at 65° to give a variety of carbinol derivatives in good to excellent yields using a mixture of [bmim][PF6] and water as the solvent. The isolation of the products was readily performed by the extraction with di-Et ether, and the Pd(OAc)2/P(1-Nap)3/[bmim][PF6]/H2O system could be easily recycled and reused six times without significant loss of catalytic activity. The authors’ system not only avoids the use of easily volatile THF or toluene as solvent but also solves the basic problem of palladium catalyst and these phosphine ligand reuse.

In some applications, this compound(3411-48-1)Reference of Tri(naphthalen-1-yl)phosphine is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 1663-45-2, is researched, Molecular C26H24P2, about Designing and synthesis of phosphine derivatives of Ru3(CO)12 – Studies on catalytic isomerization of 1-alkenes, the main research direction is trinuclear ruthenium carbonyl ethanebisphosphino complex catalyst preparation crystal structure; isomerization catalyst trinuclear ruthenium carbonyl ethanebisphosphino complex.Category: chiral-nitrogen-ligands.

A comparative investigation on the isomerization reactions of 1-alkenes to their corresponding 2-alkenes catalyzed Ru3(CO)12 (1), Ru3(CO)9(PEt3)3 (2) and Ru3(CO)10(dppe) (3), (dppe = 1,2-bis(diphenylphosphino)ethane) is described. Both the complexes of types 2 and 3 were characterized by all anal. and spectroscopic data. The mol. structure of 2 was confirmed by single-crystal x-ray anal. The nature of phosphine ligands plays an important role in the isomerization of 1-alkenes. When the chelated diphosphine was used, the internal isomerization reaction by [Ru3(CO)10(dppe)] (3) is completed relatively in less time compared to other derivatives As per the DFT calculations, the observed reaction rate for the alkene isomerization may be explained based on the relative stability of 1, 2, and 3. The CO abstraction step is highly feasible in 3, the least stable among the three, thus the reaction occurs at the highest rate. Due to the increased relative stability from 2 to 1, the reaction requires more time at elevated temperatures and the rate decreases as a consequence.

As far as I know, this compound(1663-45-2)Category: chiral-nitrogen-ligands can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

Quality Control of 1,5-Dibromopentane. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 1,5-Dibromopentane, is researched, Molecular C5H10Br2, CAS is 111-24-0, about Discovery of M-1121 as an Orally Active Covalent Inhibitor of Menin-MLL Interaction Capable of Achieving Complete and Long-Lasting Tumor Regression. Author is Zhang, Meng; Aguilar, Angelo; Xu, Shilin; Huang, Liyue; Chinnaswamy, Krishnapriya; Sleger, Taryn; Wang, Bo; Gross, Stefan; Nicolay, Brandon N.; Ronseaux, Sebastien; Harvey, Kaitlin; Wang, Yu; McEachern, Donna; Kirchhoff, Paul D.; Liu, Zhaomin; Stuckey, Jeanne; Tron, Adriana E.; Liu, Tao; Wang, Shaomeng.

Targeting the menin-MLL protein-protein interaction is being pursued as a new therapeutic strategy for the treatment of acute leukemia carrying MLL-rearrangements (MLLr leukemia). Herein, we report M-1121(I), a covalent and orally active inhibitor of the menin-MLL interaction capable of achieving complete and persistent tumor regression. M-1121 (I) establishes covalent interactions with Cysteine 329 located in the MLL binding pocket of menin and potently inhibits growth of acute leukemia cell lines carrying MLL translocations with no activity in cell lines with wild-type MLL. Consistent with the mechanism of action, M-1121 (I) drives dose-dependent down-regulation of HOXA9 and MEIS1 gene expression in the MLL-rearranged MV4;11 leukemia cell line. M-1121 (I) is orally bioavailable and shows potent antitumor activity in vivo with tumor regressions observed at tolerated doses in the MV4;11 s.c. and disseminated models of MLL-rearranged leukemia. Together, our findings support development of an orally active covalent menin inhibitor as a new therapy for MLLr leukemia.

This literature about this compound(111-24-0)Quality Control of 1,5-Dibromopentanehas given us a lot of inspiration, and I hope that the research on this compound(1,5-Dibromopentane) can be further advanced. Maybe we can get more compounds in a similar way.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 5-(4-Pyridyl)-1H-tetrazole( cas:14389-12-9 ) is researched.Application of 14389-12-9.Yang, Gao Wen; Zhang, Yuan Ting; Wu, Qi; Cao, Meng Jie; Wu, Jiao; Yue, Qiu Yan; Li, Qiao Yun published the article 《Nitrogen-rich 5-(4-pyridyl)tetrazole-2-acetic acid and its alkaline earth metal coordination polymers for potential energetic materials》 about this compound( cas:14389-12-9 ) in Inorganica Chimica Acta. Keywords: magnesium calcium strontium barium pyridyltetrazoleacetate polymer preparation thermal explosion; crystal structure magnesium calcium strontium barium pyridyltetrazoleacetate polymer. Let’s learn more about this compound (cas:14389-12-9).

Tetrazole and its derivatives with rich nitrogen atoms may be potential candidates for energetic materials. Alk. earth metal coordination compounds based on such ligands are relatively less investigated. Hpytza was prepared from 4-cyanopyridine and sodium azide, Et bromoacetate, where Hpytza = 5-(4-pyridyl)tetrazole-2-acetic acid. Hpytza and four alk. earth metal coordination polymers [Mg(pytza)2]n (1), [Ca(pytza)2(H2O)2]n·3nH2O (2), [Sr(pytza)2(H2O)2]n (3) and [Ba(pytza)2(H2O)2]n·nH2O (4) were prepared under solvothermal conditions. The thermal behavior of these compounds were characterized by the differential scanning calorimetry (DSC) and thermogravimetric-differential thermogravimetric (TG-DTG) analyses. Furthermore, the critical temperature of thermal explosion and relevant thermal parameters ΔS, ΔH, ΔG of Hpytza and polymers 1-4 were calculated, as well, indicating that these compounds are potential energetic materials.

This literature about this compound(14389-12-9)Application of 14389-12-9has given us a lot of inspiration, and I hope that the research on this compound(5-(4-Pyridyl)-1H-tetrazole) can be further advanced. Maybe we can get more compounds in a similar way.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 1,5-Dibromopentane, is researched, Molecular C5H10Br2, CAS is 111-24-0, about Effect of linker length on photo-cross-linking position mediated by click chemistry via [2 + 2]photocycloaddition, the main research direction is cyanovinylcarbazole photocross linker photocycloaddition.COA of Formula: C5H10Br2.

Ultrafast reversible DNA/RNA photo-crosslinking is a powerful tool for regulating the target strand in living cells. In particular, 3-cyanovinylcarbazole (CNVK) and 3-cyanovinylcarbazole modified by D-threoninol (CNVD) can photo-cross-link to pyrimidine bases within a few seconds of photoirradiation However, these photo-cross-linkers can only cross-link to the counter base if it is adjacent to the 5′-side (-1 position). In this study, we synthesized novel photo-cross-linkers with varying linker lengths capable of photo-crosslinking with pyrimidine bases at locations other than the -1 position via click chem. The photo-crosslinking site was dependent on linker length.

This literature about this compound(111-24-0)COA of Formula: C5H10Br2has given us a lot of inspiration, and I hope that the research on this compound(1,5-Dibromopentane) can be further advanced. Maybe we can get more compounds in a similar way.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 1,2-Bis(diphenylphosphino)ethane(SMILESS: P(CCP(C1=CC=CC=C1)C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4,cas:1663-45-2) is researched.Application In Synthesis of Bromoferrocene. The article 《Density Functional Theory Mechanistic Study of Ni-Catalyzed Reductive Alkyne-Alkyne Cyclodimerization: Oxidative Cyclization versus Outer-Sphere Proton Transfer》 in relation to this compound, is published in Organic Letters. Let’s take a look at the latest research on this compound (cas:1663-45-2).

D. functional theory mechanistic study of the nickel-catalyzed reductive alkyne-alkyne cyclodimerization with CH3OH/BEt3 unveils that, after forming a nickel-alkyne π complex, the reaction prefers outer-sphere proton transfer rather than the common alkyne-alkyne oxidative cyclization. The outperformance of aminophosphine ligand (L1) is attributed to its bidentate coordination that favors the proton transfer, the labile -NH2 and strong electron-donating -PPh2 arms and adequate Ni-P distance that allow the hydrogen transfer of the Et group of MeO-BEt3-.

This literature about this compound(1663-45-2)Quality Control of 1,2-Bis(diphenylphosphino)ethanehas given us a lot of inspiration, and I hope that the research on this compound(1,2-Bis(diphenylphosphino)ethane) can be further advanced. Maybe we can get more compounds in a similar way.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 14389-12-9, is researched, SMILESS is C1(C2=NN=NN2)=CC=NC=C1, Molecular C6H5N5Journal, CrystEngComm called New (3,4)-connected intrinsically chiral topology observed in a homochiral coordination polymer from achiral precursors, Author is Wang, Fei; Zhang, Jian; Chen, Shu-Mei; Xie, Yi-Ming; Wu, Xiao-Yuan; Chen, Shan-Ci; Yu, Rong-Min; Lu, Can-Zhong, the main research direction is copper pyridyltetrazole cyanide bridge coordination polymer solvothermal preparation; crystal structure luminescence copper pyridyltetrazole cyanide bridge coordination polymer; NLO homochirality copper pyridyltetrazole cyanide bridge coordination polymer.SDS of cas: 14389-12-9.

An unpredicted (3,4)-connected topol. with intrinsic chirality present in a homochiral coordination polymer [Cu2(L)CN]n (1; L = 5-(4-pyridyl)tetrazole) was first shown here, which reveals a new possibility for the construction of lowly-connected chiral framework materials with potential applications.

This literature about this compound(14389-12-9)SDS of cas: 14389-12-9has given us a lot of inspiration, and I hope that the research on this compound(5-(4-Pyridyl)-1H-tetrazole) can be further advanced. Maybe we can get more compounds in a similar way.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis