Extracurricular laboratory: Synthetic route of 3411-48-1

The article 《A simple and practical protocol for the palladium-catalyzed cross-coupling of boronic acids with methyl iodide》 also mentions many details about this compound(3411-48-1)Synthetic Route of C30H21P, you can pay attention to it, because details determine success or failure

Synthetic Route of C30H21P. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: Tri(naphthalen-1-yl)phosphine, is researched, Molecular C30H21P, CAS is 3411-48-1, about A simple and practical protocol for the palladium-catalyzed cross-coupling of boronic acids with methyl iodide.

A combination of palladium acetate and tri-1-naphthylphosphine was a highly efficient catalyst system for the cross-coupling of arylboronic acids with Me iodide at room temperature The new process allows for a convenient introduction of Me groups into various functionalized arenes under mild conditions. Thus, tri-1-naphthylphosphine/palladium acetate catalyzed cross-coupling of p-nitrophenylboronic acid with Me iodide in the presence of K3PO4 in H2O/THF gave 89% 4-nitrotoluene.

The article 《A simple and practical protocol for the palladium-catalyzed cross-coupling of boronic acids with methyl iodide》 also mentions many details about this compound(3411-48-1)Synthetic Route of C30H21P, you can pay attention to it, because details determine success or failure

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis