Category: chiral-nitrogen-ligands. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: 1,5-Dibromopentane, is researched, Molecular C5H10Br2, CAS is 111-24-0, about Synthesis of alkyl/aryl linked binuclear silver(I)-N-Heterocyclic carbene complexes and evaluation of their antimicrobial, hemolytic and thrombolytic potential. Author is Habib, Aqsa; Iqbal, Muhammad Adnan; Bhatti, Haq Nawaz; Kamal, Amna; Kamal, Shagufta.
A new series of N-Heterocyclic carbene based ligands and their silver(I) complexes was obtained and tested in vitro on three bacterial strains (Bacillus subtillis, Bacillus cereus and Macrococcus brunensis) to assess their antibacterial potential. Hemolytic and thrombolytic activities of ligands and complexes on normal mouse erythrocytes were also assessed. In vitro antibacterial study of ligands and complexes revealed that the complexes are relatively more antibiotically active than the ligands. Zones of inhibition and MIC values revealed that B. subtillis is more sensitive to complexes than B. cereus and M. brunensis while reverse is the case for NHC salts. Hemolytic and thrombolytic assays revealed that the compounds are safe to mouse blood for pre-clin. trials.
The article 《Synthesis of alkyl/aryl linked binuclear silver(I)-N-Heterocyclic carbene complexes and evaluation of their antimicrobial, hemolytic and thrombolytic potential》 also mentions many details about this compound(111-24-0)Category: chiral-nitrogen-ligands, you can pay attention to it, because details determine success or failure
Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis