Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Recommanded Product: 4-Nitrophenyl chloroformate, 7693-46-1, Name is 4-Nitrophenyl chloroformate, molecular formula is C7H4ClNO4, belongs to chiral-nitrogen-ligands compound. In a document, author is Abadie, Marc-Antoine, introduce the new discover.
Development of Chiral C-2-Symmetric N-Heterocyclic Carbene Rh(I) Catalysts through Control of Their Steric Properties
Chiral square-planar Rh(I) complexes based on new C-2-symmetric NHC ligands have been synthesized selectively in a few steps as single diastereoisomers. These chiral precatalysts were applied to the asymmetric transfer hydrogenation of 1-phenylpropanone and to the 1,2-addition of arylboronic acids to aldehydes. We demonstrated a proper functionalization of the aromatic rings connected to the nitrogen atoms of the NHC ligand improved significantly the asymmetric induction of the chiral Rh(I) NHC catalysts. Bulky substituents allowed a better control of the steric features of the catalyst quadrants because they behaved as conformational and chirality relays of the NHC chiral backbone.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 7693-46-1. Recommanded Product: 4-Nitrophenyl chloroformate.
Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis¡ªI. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
,Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis