In heterogeneous catalysis, catalysts provide a surface to which reactants bind in a process of adsorption. Computed Properties of C20H13N3O2, Name is 3,4-Di(1H-indol-3-yl)-1H-pyrrole-2,5-dione, belongs to chiral-nitrogen-ligands compound, is a common compound. Computed Properties of C20H13N3O2Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. In an article, authors is Boiteau, Jean-Guy, once mentioned the new application about Computed Properties of C20H13N3O2.
Development of a Kilogram-Scale Synthesis of a Novel MC1R Agonist
Herein, we report the kilogram-scale synthesis of CD08108, a novel MC1R agonist. This synthesis has been developed to produce the first batches of this compound for preclinical and clinical studies. Two amido couplings were used to synthesize the backbone of the API. Improvements have been made to isolate crystalline intermediates and to remove all column chromatographic steps. Crystallization of the final API was monitored by DSC in-process control during slurry ripening of the amorphous suspension of the hydrochloride salt.
Future efforts will undeniably focus on the diversification of the new catalytic transformations. These may comprise an expansion of the substrate scope from aromatic and heteroaromatic compounds to other hydrocarbons. Computed Properties of C20H13N3O2, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 119139-23-0, in my other articles.
Reference：
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis