The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 2-Aminoquinazolin-4(3H)-one(SMILESS: O=C1NC(N)=NC2=C1C=CC=C2,cas:20198-19-0) is researched.Quality Control of 2-Aminoquinazolin-4(3H)-one. The article 《Comparative activity of 2-thioxo-, 2-(methylthio)-, 2-(methylseleno)-, and 2-amino-4-quinazolinones toward aromatic amines》 in relation to this compound, is published in O’zbekiston Kimyo Jurnali. Let’s take a look at the latest research on this compound (cas:20198-19-0).
Reactions of title compounds I and II (R = SMe, SeMe, NH2) with arylamines gave II [R = (un)substituted phenyl] were examined The reactivity of the 2-substituents decreased in the following order: SeMe > SMe > NH2 > C:S.
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Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis