Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Recommanded Product: 2,4-Dimethylpyridine. Introducing a new discovery about 108-47-4, Name is 2,4-Dimethylpyridine
Introduction of Ether Groups onto Electron-Deficient Nitrogen-Containing Heteroaromatics Using Radical Chemistry under Transition-Metal-Free Conditions
Electron-deficient nitrogen-containing heteroaromatics, such as quinoline, isoquinoline, and pyridine, were treated with benzoyl peroxide in dioxane, tetrahydropyran, tetrahydrofuran, diethyl ether, and dipropyl ether at 80C to form alkylated nitrogen-containing heteroaromatics in good yields under transition-metal-free conditions. This method was successfully applied to the preparation of lariat aza-crown ethers using 18-crown-6 or 15-crown-5 with quinoline and isoquinoline in the presence of benzoyl peroxide in good yields under irradiation conditions with a Hg lamp.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Recommanded Product: 2,4-Dimethylpyridine, you can also check out more blogs about108-47-4
Reference£º
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis¡ªI. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis