Synthetic Route of 126456-43-7, Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.126456-43-7, Name is (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol, molecular formula is C9H11NO. In a article,once mentioned of 126456-43-7
The present invention relates to a class of tridentate ligands and related ligand PNHO in asymmetric hydrogenation and its similar application of the catalyst in the reaction. The present invention discloses a novel three nitro phosphine oxygen ligand is the 1st example of the ferrocene-containing plane under nitro phosphine oxygen ligand, and successfully applied to is simple an aromatic ketone, alpha? Hydroxy ketone, beta? Ketoesters efficient high selective asymmetric hydrogenation reaction and the like. A tridentate ligands compared with other advantages, the synthetic route of ligand of this type is extremely simple, low cost, easy large-scale synthesis, air stable, the asymmetric hydrogenation of the carbon-oxygen double bond reaction demonstrate the high activity and high selectivity. (by machine translation)
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Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis