108-47-4, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 108-47-4, Name is 2,4-Dimethylpyridine,introducing its new discovery.
Catalytic Reactions of Pyridines. V. Alkylation of alpha-, beta-, and gamma-Picolines with Alcohols catalyzed by Ammonium Halides
A new method was found for the homogeneous liquid-phase alkylation of alpha-, beta-, and gamma-picolines with either methanol or ethanol.Addition of a catalytic amount of an ammonium halide to a mixture of a picoline and an alcohol resulted in a great increase in the yields of both side-chain and alpha-alkylated derivatives of the starting picoline when the reaction was carried out at 320-335 deg C in an atmosphere of nitrogen.The higher the reaction temperature, the greater the yields of side-chain alkylated derivatives became.In practice, this alkylation gave 2-ethylpyridine, and 2,6-lutidine from alpha-picoline with methanol, 3-ethylpyridine and 2,5-lutidine from beta-picoline from methanol, 4-ethylpyridine and 2,4-lutidine from gamma-picoline with methanol, 2-propylpyridine and 2-ethyl-6-methylpyridine from alpha-picoline with ethanol, 2-ethyl-5-methylpyridine from beta-picoline with ethanol, and 4-propylpyridine and 2-ethyl-4-methylpyridine from gamma-picoline with ethanol.Keywords-alkylation; catalyst; ammonium halide; alpha-picoline; beta-picoline; gamma-picoline; ethylpyridine; propylpyridine; methanol; ethanol
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 108-47-4, and how the biochemistry of the body works.108-47-4
Reference£º
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis¡ªI. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis