In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called 6-Chloro-N-(pyridin-4-ylmethyl)pyridine-3-sulfonamide, published in 2013-12-31, which mentions a compound: 6684-39-5, mainly applied to crystal structure chloropyridinylmethylpyridinesulfonamide; mol structure chloropyridinylmethylpyridinesulfonamide; hydrogen bond chloropyridinylmethylpyridinesulfonamide, COA of Formula: C5H3Cl2NO2S.
In 6-chloro-N-(pyridin-4-ylmethyl)pyridine-3-sulfonamide, C11H10ClN3O2S, the dihedral angle between the pyridine rings is 46.85(12)°. The N atom of the chloropyridine ring is anti to the N-H bond. In the crystal, mols. are linked through N-H···N H bonds into zigzag chains parallel to [001] with a C(7) graph-set motif. Crystallog. data are given.
After consulting a lot of data, we found that this compound(6684-39-5)COA of Formula: C5H3Cl2NO2S can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis