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The present invention is directed toward substituted hydroxyethylene compounds of formula (XII) useful in treating Alzheimer’s disease and other similar diseases.
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Reference：
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis