SDS of cas: 1663-45-2. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: 1,2-Bis(diphenylphosphino)ethane, is researched, Molecular C26H24P2, CAS is 1663-45-2, about Carboxylation of a Palladacycle Formed via C(sp3)-H Activation: Theory-Driven Reaction Design. Author is Kanna, Wataru; Harabuchi, Yu; Takano, Hideaki; Hayashi, Hiroki; Maeda, Satoshi; Mita, Tsuyoshi.
Theory-driven organic synthesis is a powerful tool for developing new organic transformations. A palladacycle(II), generated from 8-methylquinoline via C(sp3)-H activation, is frequently featured in the scientific literature, albeit that the reactivity toward CO2, an abundant, inexpensive, and non-toxic chem., remains elusive. Authors have theor. discovered potential carboxylation pathways using the artificial force induced reaction (AFIR) method, a d.-functional-theory (DFT)-based automated reaction path search method. The thus obtained results suggest that the reduction of Pd(II) to Pd(I) is key to promote the insertion of CO2. Based on these computational findings, they employed various one-electron reductants, such as Cp*2Co, a photoredox catalyst under blue LED irradiation, and reductive electrolysis ((+)Mg/(-)Pt), which afforded the desired carboxylated products in high yields. After screening phosphine ligands under photoredox conditions, they discovered that bidentate ligands such as dppe promoted this carboxylation efficiently, which was rationally interpreted in terms of the redox potential of the Pd(II)-dppe complex as well as on the grounds of DFT calculations They are convinced that these results could serve as future guidelines for the development of Pd(II)-catalyzed C(sp3)-H carboxylation reactions with CO2.
This literature about this compound(1663-45-2)SDS of cas: 1663-45-2has given us a lot of inspiration, and I hope that the research on this compound(1,2-Bis(diphenylphosphino)ethane) can be further advanced. Maybe we can get more compounds in a similar way.
Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis