In an article, author is Karahan, Seda, once mentioned the application of 3483-12-3, COA of Formula: C4H10O2S2, Name is DL-2,3-Dihydroxy-1,4-butanedithiol, molecular formula is C4H10O2S2, molecular weight is 154.251, MDL number is MFCD00004877, category is chiral-nitrogen-ligands. Now introduce a scientific discovery about this category.
Squaramide catalyzed alpha-chiral amine synthesis
Enantiomerically pure alpha-chiral amines, have been commonly utilized as resolving agents and chiral auxiliaries and are currently found in 40% of active pharmaceutical ingredients. Hence, development of highly stereoselective metal-free protocols regarding atom-economy and large-scale applications becomes a major issue. In this respect, chiral bifunctional H-bonding squaramides have been successfully applied for both amine synthesis and functionalization of amines in the last decade. This survey summarizes asymmetric synthesis of chiral amines by various carbon-carbon and carbon-nitrogen bond formation with squaramide catalysis as a particular focus of interest. (C) 2018 Published by Elsevier Ltd.
If you are interested in 3483-12-3, you can contact me at any time and look forward to more communication. COA of Formula: C4H10O2S2.
Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis¡ªI. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
,Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis