Category: 111-24-0

Quality Control of 1,5-Dibromopentane. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 1,5-Dibromopentane, is researched, Molecular C5H10Br2, CAS is 111-24-0, about Accordion-like effect of flexible organic structure-directing agents in the synthesis of ferrierite zeolite. Author is Almeida, Ramon K. S.; Perez-Pariente, Joaquin; Gomez-Hortiguela, Luis.

Ferrierite zeolite was synthesized by a co-structure-directing route using a highly flexible diquaternary ammonium cation (N,N’-bis-triethylpentanediyldiammonium) as a structure directing agent in combination with tetramethylammonium as a small co-structure-directing agent. Strong alterations of the 13C NMR bands of the bulky organic dication upon confinement within the ferrierite framework suggest a change of conformation driven by host-guest interactions. A combination of mol. mechanics and DFT calculations of the theor. 13C NMR chem. shifts allowed to explain the observed differences in the NMR bands of the dication in solution and when hosted in ferrierite: upon confinement, the flexible dication needs to squeeze through the flexible pentyl chain which locates along the 10 MR ferrierite channels in order to host the two bulky tri-Et ammonium groups in adjacent intersections with 8 MR channels. Our work suggests that highly flexible cations, usually considered as less convenient organic structure-directing agents because of low specificity, have the advantage of being able to properly fit with different zeolite cell dimensions through an accordion-like effect by squeezing or stretching their flexible chains.

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Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Synthesis called N -Methylated 1,8-Diaminonaphthalenes as Bifunctional Nucleophiles in Reactions with α,ω-Dihalogenoalkanes: A Facile Route to Heterocyclic and Double Proton Sponges, Author is Kolupaeva, Ekaterina V.; Ozeryanskii, Valery A.; Pozharskii, Alexander F., which mentions a compound: 111-24-0, SMILESS is BrCCCCCBr, Molecular C5H10Br2, Electric Literature of C5H10Br2.

The reaction of 1-dimethylamino-8-(methylamino)naphthalene with 1,3-dibromopropane chemoselectively leaded to the product of N, N’-heterocyclization, while in the case of 1,4-dibromobutane and 1,2-bis(bromomethyl)benzene the process resulted in heterocyclization onto the same nitrogen atom with the formation of previously unknown 1-dimethylamino-8-pyrrolidino- and 1-dimethylamino-8-isoindolino-naphthalenes. The same reactions conducted without adding any auxiliary base leaded to the formation of N, N’-linked double proton sponges as a new type of polynitrogen organic receptor. Proceeding as a sequence of quaternization-demethylation-cyclization steps, this heterocyclization process was used to construct six-membered rings (piperidino, morpholino), albeit in lower yields. The ability of 1,2-dibromoethane to brominate N-alkylated 1,8-diaminonaphthalenes was described. It is shown for the first time that a com. available 1,8-bis(dimethylamino)naphthalene (DMAN) can be used as a starting material in a heterocyclization reaction, which via a one-pot approach and in a short time can be converted into 1,5-dimethylnaphtho[1,8- bc]-1,5-diazacyclooctane or 1-dimethylamino-8-(pyrrolidin-1-yl)naphthalene.

Here is a brief introduction to this compound(111-24-0)Electric Literature of C5H10Br2, if you want to know about other compounds related to this compound(111-24-0), you can read my other articles.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Stereoselective Oxidative Bioconjugation of Amino Acids and Oligopeptides to Aldehydes, published in 2020-10-05, which mentions a compound: 111-24-0, Name is 1,5-Dibromopentane, Molecular C5H10Br2, Application of 111-24-0.

The first stereoselective, near-equimolar, and metal-free oxidative bioconjugation of amino acids and oligopeptides to aldehydes is presented. Based on a newly developed organocatalytic oxidative concept, the C-terminal and side-chain carboxylic acid functionalities of amino acids and oligopeptides are shown to couple in a stereoselective manner to α-branched aldehydes catalyzed by a chiral primary amine and a quinone as oxidizing agent. The oxidative coupling generally proceeds in high yield. For aspartic acid, selective coupling of the side-chain, or the C-terminal carboxylic acid, is demonstrated depending on the protection strategy. The stereoselective, oxidative bioconjugation concept is extended to a series of oligopeptides where coupling to carboxylic acid functionalities is presented. Bioorthogonal linker mols. for further functionalization are obtained by merging the oxidative coupling strategy with the click concept. It is demonstrated that the configuration of the new stereocenter is determined exclusively by the organocatalyst.

If you want to learn more about this compound(1,5-Dibromopentane)Application of 111-24-0, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(111-24-0).

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

HPLC of Formula: 111-24-0. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 1,5-Dibromopentane, is researched, Molecular C5H10Br2, CAS is 111-24-0, about Approaches to the synthesis of dicarboxylic derivatives of bis(pyrazol-1-yl)alkanes. Author is Burlutskiy, Nikita P.; Potapov, Andrei S..

Carboxylation of bis(pyrazol-1-yl)alkanes by oxalyl chloride was studied. It was found that 4,4′-dicarboxylic derivatives of substrates with electron-donating Me groups and short linkers (from one to three methylene groups) can be prepared using this method. Longer linkers lead to significantly lower product yields, which was probably due to instability of the intermediate acid chlorides that are initially formed in the reaction with oxalyl chloride. Thus, bis(pyrazol-1-yl)methane gave only monocarboxylic derivative even with a large excess of oxalyl chloride and prolonged reaction duration. An alternative approach involves the reaction of Et 4-pyrazolecarboxylates with dibromoalkanes in a superbasic medium (potassium hydroxide-dimethyl sulfoxide) and was suitable for the preparation of bis(4-carboxypyrazol-1-yl)alkanes with both short and long linkers independent of substitution in positions 3 and 5 of pyrazole rings. The obtained dicarboxylic acids are interesting as potential building blocks for metal-organic frameworks.

If you want to learn more about this compound(1,5-Dibromopentane)HPLC of Formula: 111-24-0, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(111-24-0).

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

Category: chiral-nitrogen-ligands. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 1,5-Dibromopentane, is researched, Molecular C5H10Br2, CAS is 111-24-0, about Synthesis and Antileishmanial Evaluation of Arylimidamide-Azole Hybrids Containing a Phenoxyalkyl Linker.

A mol. hybridization approach was employed where arylimidamide and azole groups were separated by phenoxyalkyl linkers in an attempt to capitalize on the favorable antileishmanial properties of both series I [X = Y = Z = CH, N; n = 2, 3, 4, 5, 6, 8, 10; R1 = R2 = H, OMe, Cl, OEt, Oi-Pr] and II. Among the target compounds synthesized I, a greater antileishmanial potency against intracellular Leishmania donovani were observed as the linker length increased from two to eight carbons and when an imidazole ring was employed as the terminal group compared to a 1,2,4-triazole group. Compound I [X = CH, Y = Z = N, R1 = H, R2 = Oi-Pr] displayed activity against L. donovani intracellular amastigotes with an IC50 value of 0.53μM. When tested in a murine visceral leishmaniasis model, compound I [X = Y = Z = CH, N; n = 2, 3, 4, 5, 6, 8, 10; R1 = R2 = H, OMe, Cl, OEt, Oi-Pr] at a dose of 75 mg/kg/day p.o. for five consecutive days resulted in a modest 33% decrease in liver parasitemia compared to the control group, which indicated that further optimization of these mols. were needed. While potent hybrid compounds bearing an imidazole terminal group were also strong inhibitors of recombinant CYP51 from L. donovani, as assessed by a fluorescence-based assay, addnl. targets were likely to play an important role in the antileishmanial action of these compounds

If you want to learn more about this compound(1,5-Dibromopentane)Category: chiral-nitrogen-ligands, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(111-24-0).

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

Formula: C5H10Br2. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 1,5-Dibromopentane, is researched, Molecular C5H10Br2, CAS is 111-24-0, about Photosensitizer with High Efficiency Generated in Cells via Light-Induced Self-Oligomerization of 4,6-Dibromothieno[3,4-b]thiophene Compound Entailing a Triphenyl Phosphonium Group. Author is Wang, Lingna; Huang, Yanyan; Yu, Yingjie; Zhong, Huifei; Xiao, Haihua; Zhang, Guanxin; Zhang, Deqing.

Photodynamic therapy (PDT) has emerged as an attractive alternative in cancer therapy, but therapeutic effects suffer from low photosensitizing efficiency and poor retention of photosensitizes in cancer cells. This paper reports the photosensitizers which show absorption and emission in the long-wavelength region and high photosensitizing efficiency can be formed in situ in cells from 4,6-dibromothieno[3,4-b]thiophene derivative (TT-5-P) after white light irradiation The self-oligomerization of TT-5-P is uptaken in cells upon light irradiation-induced cell apoptosis simultaneously and efficiently. In addition, the formation of oligomers (TT-5-Ps) enhances the retention time in cells remarkably, which is advantageous for boosting the photodynamic therapy efficiency. Moreover, the selectivity toward tumor cells of TT-5-P can be improved obviously via the formation of complex of TT-5-P with albumin. This in situ photoinduced self-oligomerization strategy can be utilized to design effective biomaterials for long-term imaging and improved therapy.

Here is a brief introduction to this compound(111-24-0)Formula: C5H10Br2, if you want to know about other compounds related to this compound(111-24-0), you can read my other articles.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

Computed Properties of C5H10Br2. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 1,5-Dibromopentane, is researched, Molecular C5H10Br2, CAS is 111-24-0, about Study of the interaction between ninhydrin and chromium(III)-amino acid in an aqueous-micellar system: Influence of gemini surfactant micelles. Author is Kumar, Dileep; Abdul Rub, Malik.

Chromium(III)-amino acid ([Cr(III)-His]2+) and ninhydrin in an aqueous-micellar system were combined in acetate buffer at 353 K and analyzed by UV-vis spectroscopy. Dimeric geminis (16-s-16, s, spacer, = 4 to 6) were chosen as a surfactant and their influence on the reaction rate was determined To show this behavior of gemini surfactants on rate constant (kψ), kψ was plotted against different surfactant concentrations kψ increases with increasing [16-s-16] (at concentrations lesser than their cmc values, segment I) and leveling-off regions attain (concentration upto 400 × 10-5 mol dm-3, segment II). Later, [16-s-16] generates a third region of increasing kψ at higher [16-s-16] ([16-s-16] > 400 × 10-5 mol dm-3, segment III). The uncommon plot behavior of kψ vs. [16-s-16] was revealed, effectively, by utilizing a pseudo-phase model of micellar activity. Critical micellar concentration of pure gemini surfactants, as well as their mixed solution with reactants, was determined by conductometry. Based on the data, various thermodn. parameters and binding constants were calculated under different exptl. reaction conditions.

Here is a brief introduction to this compound(111-24-0)Computed Properties of C5H10Br2, if you want to know about other compounds related to this compound(111-24-0), you can read my other articles.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis