The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 1,5-Dibromopentane, is researched, Molecular C5H10Br2, CAS is 111-24-0, about Effect of linker length on photo-cross-linking position mediated by click chemistry via [2 + 2]photocycloaddition, the main research direction is cyanovinylcarbazole photocross linker photocycloaddition.COA of Formula: C5H10Br2.
Ultrafast reversible DNA/RNA photo-crosslinking is a powerful tool for regulating the target strand in living cells. In particular, 3-cyanovinylcarbazole (CNVK) and 3-cyanovinylcarbazole modified by D-threoninol (CNVD) can photo-cross-link to pyrimidine bases within a few seconds of photoirradiation However, these photo-cross-linkers can only cross-link to the counter base if it is adjacent to the 5′-side (-1 position). In this study, we synthesized novel photo-cross-linkers with varying linker lengths capable of photo-crosslinking with pyrimidine bases at locations other than the -1 position via click chem. The photo-crosslinking site was dependent on linker length.
This literature about this compound(111-24-0)COA of Formula: C5H10Br2has given us a lot of inspiration, and I hope that the research on this compound(1,5-Dibromopentane) can be further advanced. Maybe we can get more compounds in a similar way.
Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis