Application of 111-24-0. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 1,5-Dibromopentane, is researched, Molecular C5H10Br2, CAS is 111-24-0, about Efficient synthesis and characterization of novel bis-heterocyclic derivatives and benzo-fused macrocycles containing oxazolone or imidazolone subunits. Author is Sanad, Sherif M. H.; Mekky, Ahmed E. M..
Bis(3-(arylthiomethyl)benzaldehydes), linked to aliphatic spacers via ethers, were prepared and used as key synthons for the bis(2-phenyloxazol-5(4H)-ones) I [R = 4-Me-PhS, 4-Cl-PhS, 4-NO2-PhS; R1 = 2-phenyloxazol-5(4H)-one-4-methylene] via their reaction with benzoylglycine. Bis(oxazol-5(4H)-ones) I were reacted with the appropriate aromatic or heterocyclic amines to afford a novel series of bis(2-phenylimidazol-4-ones) II [X = 4-Me-Ph, 4-Cl-Ph] and their related hybrids with benzo[d]thiazole and pyrimidine-2,4(1H,3H)-dione. Moreover, bis(oxazol-5(4H)-ones) I [R = 4-Me-PhS, 4-Cl-PhS; R1 = 2-phenyloxazol-5(4H)-one-4-methylene] reacted with (4-aminobenzoyl)glycine to afford bis[(4-(5-oxo-1H-imidazol-1-yl)benzoyl)glycine] derivatives II [R = 4-Me-PhS, 4-Cl-PhS; X = 4-C(O)NHCH2COOH-Ph] followed by their reaction with anisaldehyde gave corresponding bis(5-oxo-1H-imidazol-1-yloxazol-5(4H)-one) hybrids III [R2 = 4-(4-OMe-phenylmethylene)-oxazol-5(4H)-one]. Furthermore, bis(3-(arylthiomethyl)benzaldehydes) I [R = 4-Me-PhS, 4-Cl-PhS; R1 = CHO] were reacted with 2,2′-(terephthaloylbis(azanediyl))diacetic acid to give benzo-fused macrocycles IV [Y = O] containing oxazolone subunits which reacted with aromatic amines to give benzo-fused macrocycles IV [Y = 4-Me-Ph-N, 4-Cl-Ph-N] containing imidazolone subunits.
After consulting a lot of data, we found that this compound(111-24-0)Application of 111-24-0 can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis