Discovery of 2,4-Dimethylpyridine

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Reference of 108-47-4, In homogeneous catalysis, catalysts are in the same phase as the reactants. Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 108-47-4, Name is 2,4-Dimethylpyridine, molecular formula is C7H9N. In a Article，once mentioned of 108-47-4

Cationic molybdenum imido alkylidene complexes

Addition of 1 equiv of [HNMe2Ph]BAr4F (ArF = 3,5-(CF3)2C6H3) to Mo(NAr)(CHCMe2Ph)(Pyrrolide)2 (Pyrrolide = parent pyrrolide (Pyr) or 2,5-dimethylpyrrolide (Me2Pyr)) species in THF produced [Mo(NAr)(CHCMe2Ph)(Pyrrolide)(THF)xBAr 4F species (x = 2 for Me2Pyr (1b) or 3 (1a) for Pyr; Ar = 2,6-diisopropylphenyl). [Mo(NAr)(CHCMe2Ph)(Me 2Pyr)(2,4-lutidine)]BAr4F (1c) was formed upon addition of 2,4-lutidine to [Mo(NAr)(CHCMe2Ph)(Me2Pyr) (THF)2]BAr4F (1b). Addition of 1 equiv of hexafluoro-tert-butanol to 1a produced (Mo(NAr)(CHCMe2Ph)[OC(CF 3)2Me](THF)3)BArP4F(3a), while [Mo(NAr)(CHCMe2Ph)[OCMe(CF3)2](THF) 2)BAr4F (3b) was obtained similarly through addition of hexafluoro-tert-butanol to 1b. Similar reactions produced unstable [Mo(NAr)(CHCMe2Ph)(O-2,6-i-Pr2C6H 3)(THF)]BAr4F (3c) and [Mo(NAr)(CHCMe 2Ph)(OAdamantyl)(THF)2]BAr4F (3d). Treatment of 1b with 2 equiv of 2,6-diisopropylphenol yielded [Mo(NAr)(CH 2CMe2Ph)(O-2,6-i-Pr2C6H 3)2]BAr4F (4). Compound 3a reacts with ethylene to yield {Mo(NAr)(CH2CH2)[OC(CF 3)2Me](THF)3)BAr4F (6). The reaction between Mo(NAr)(CHCMe2Ph)(OTf)2(dme) and 2 equiv of Li(MesPyr) (MesPyr = 2-mesitylpyrrolide) gave Mo(NAr)(CHCMe 2Ph)(MesPyr)2 (2), but no cationic species could be prepared that contain 2-mesitylpyrrolide. Compounds 1a, 1c, 2, 3a, 4, and 6 were characterized crystallographically.

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Reference：
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis