Reference of Tri(naphthalen-1-yl)phosphine. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: Tri(naphthalen-1-yl)phosphine, is researched, Molecular C30H21P, CAS is 3411-48-1, about Palladium-catalyzed vinylic substitution with highly activated aryl halides. Author is Ziegler, Carl B. Jr.; Heck, Richard F..
Aryl bromides with strongly electron-donating substituents generally do not undergo the Ph3P-Pd(OAc)2-catalyzed vinylic substitution reaction in acceptable yields. Competing formation of tetraarylphosphonium salts from the aryl bromide and, in some cases, the reduction of the aryl bromide to the arene occur. Significant improvements in yield are obtained when (o-MeC6H4)3P is used instead of Ph3P. As good or even better results are obtained using the corresponding aryl iodide instead of the bromide and using Pd(OAc)2 without a phosphine as the catalyst.
There is still a lot of research devoted to this compound(SMILES：C1=CC2=C(C=C1)C(=CC=C2)P(C1=CC=CC2=C1C=CC=C2)C1=CC=CC2=C1C=CC=C2)Reference of Tri(naphthalen-1-yl)phosphine, and with the development of science, more effects of this compound(3411-48-1) can be discovered.
Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis