Reference of 3483-12-3, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 3483-12-3, Name is DL-2,3-Dihydroxy-1,4-butanedithiol, SMILES is O[C@@H]([C@H](O)CS)CS, belongs to chiral-nitrogen-ligands compound. In a article, author is Groso, Emilia J., introduce new discover of the category.
3-Aryl-2,5-Dihydropyrroles via Catalytic Carbonyl-Olefin Metathesis
Herein, we describe the development of a synthetic strategy toward chiral 3-pyrrolines based on the design principle of iron(III)-catalyzed carbonyl-olefin metathesis. This approach takes advantage of commercially available amino acids as chiral pool reagents and FeCl3 as a Lewis acid catalyst. Our strategy is characterized by its operational simplicity, mild reaction conditions, and functional group tolerance. Investigations show that an electron deficient nitrogen protecting group overcomes limitations arising from competitive binding of the Lewis acid catalyst to unfavorable Lewis basic sites, which ultimately enables catalytic turnover.
Reference of 3483-12-3, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 3483-12-3 is helpful to your research.
Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis¡ªI. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
,Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis