Reference of 126456-43-7, In homogeneous catalysis, catalysts are in the same phase as the reactants. Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 126456-43-7, Name is (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol, molecular formula is C9H11NO. In a Article，once mentioned of 126456-43-7
New chiral ligands, (S,R,S)-1, (S,S,S)-1, (S,S,R)-1, (S,R,R)-1, (R,R,R)-1, (R,R,S)-1, (R,S,S)-1, (R,S,R)-1, (S,R,S)-2, (S,S)-3 and (R,S)-4 with diverse stereogenic centers arising from various diastereomeric combinations of aminoalcohol functionality with (R)- and (S)-1,1-binaphthol, were prepared and characterized. Catalytically active Ti complexes were generated insitu in the presence of water for the enantioselective ring-opening reaction of meso-stilbene oxide, cyclohexene oxide, cyclopentene oxide, and cis-butene oxide with different anilines as nucleophile. Significantly, catalysts Ti-(S,R,S)-1 and Ti-(R,S,S)-1 (15mol%) produced syn-beta-amino alcohols of meso-stilbene oxide with (1S,2S) and (1R,2R) configuration respectively in excellent yields (>98%) and enantioselectivities (ee value >99%) in 10h at room temperature. However, aliphatic/cyclic epoxides with aniline gave better performance with the catalyst Ti-(S,R,R)-1. The complex Ti-(S,R,S)-1 was successfully subjected to catalyst recovery and recyclability experiments over 6 cycles in the asymmetric ring-opening of meso-stilbene oxide with aniline with retention of performance.
Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. In my other articles, you can also check out more blogs about 126456-43-7
Reference：
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis