Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 4767-03-7, Name is 3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoic acid, molecular formula is C5H10O4, belongs to chiral-nitrogen-ligands compound. In a document, author is Hua, Ting-Bi, introduce the new discover, Recommanded Product: 4767-03-7.
Recent advances in asymmetric synthesis of 2-substituted indoline derivatives
Enantiomerically pure 2-substituted indolines are an important class of nitrogen heterocycles that occur frequently in many alkaloid natural products and biologically active compounds. Consequently, the synthesis of such skeletons is of great significance. The past years have witnessed a number of remarkable advances in the development of efficient strategies to construct this class of chiral compounds. This review summarizes the recent advances in asymmetric synthesis of 2-substituted indoline derivatives. Due to the limitation of the length, this review only summarizes those works published from January of 2012 to January of 2019. Meanwhile, methods towards synthesis of fused and spirocyclic indolines will not be discussed in this review. (C) 2019 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 4767-03-7. Recommanded Product: 4767-03-7.
Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis¡ªI. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
,Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis