Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 5-(4-Pyridyl)-1H-tetrazole, is researched, Molecular C6H5N5, CAS is 14389-12-9, about A rapid and novel method for the synthesis of 5-substituted 1H-tetrazole catalyzed by exceptional reusable monodisperse Pt NPs@AC under the microwave irradiation.Application of 14389-12-9.
A series of 5-substituted 1H-tetrazoles I (R = 4-O2NC6H4, 4-BrC6H4, 4-MeC6H4, etc.) were synthesized in DMF by the [3 + 2] cycloaddition reaction under the effect of microwave irradiation (10-30 min, fixed mode, 90 °C, 140 W) in the presence of highly efficient superior catalyst. For this reaction, different aromatic nitriles with the sodium azide were used and superior monodisperse (Md) platinum nanoparticles (Pt NPs) decorated on activated carbon (AC) served as a catalyst. Md-Pt NPs@AC were reproducibly and easily produced by double solvent reduction of PtCl4 in room temperature and characterized by transmission electron microscopy (TEM), the high resolution electron micrograph (HRTEM), X-ray diffraction (XRD), at. force microscopy (AFM) and XPS. The sum of their results shows the formation of highly crystalline and colloidally stable Md-Pt NPs@AC. The catalytic performance of these new NPs were investigated for the synthesis of 5-substituted 1H-tetrazoles, in which they were found to be exceptional reusable, isolable, stable and highly efficient heterogeneous catalyst. All prepared tetrazole products were obtained with perfect yield by using current heterogeneous catalyst.
Although many compounds look similar to this compound(14389-12-9)Application of 14389-12-9, numerous studies have shown that this compound(SMILES:C1(C2=NN=NN2)=CC=NC=C1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis