The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Visible and ultraviolet absorption of some derivatives of 2,4-dioxotetrahydroquinazoline and related open-chain compounds》. Authors are Grammaticakis, Panos.The article about the compound:2-Aminoquinazolin-4(3H)-onecas:20198-19-0,SMILESS:O=C1NC(N)=NC2=C1C=CC=C2).Name: 2-Aminoquinazolin-4(3H)-one. Through the article, more information about this compound (cas:20198-19-0) is conveyed.
The visible and ultraviolet light absorption of derivatives of 4-oxotetrahydroquinazoline (I) and of anthranilic acid are measured. Curves for the following derivatives of I acid are measured. Curves are given for the following derivatives of I: 2-oxo-, m. 263-5°, 1-methyl-2-oxo-, m. 288-90°, 3-phenyl-2-oxo-, m. 278°, 2-thio-, m.inst. 315°, 2-imino- m.inst. 310°, and 3-phenyl-2-thio-, m.inst. 307°; ο-H2NOCC6H4NHCONH2, m.inst. 218°; ο-MeO2CC6H4NHCONH2, m.inst. 350°; ο-MeO2CC6H4NHCSNH2, m.inst. 288°; and the following ο-substituted PhNHCONHPh: ο-CONH2, m.inst. 239°, ο-COOH, m.inst. 235°, ο-CO2Me, m. 143-4°, and ο-CN, m. 177°.
As far as I know, this compound(20198-19-0)Name: 2-Aminoquinazolin-4(3H)-one can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis