Chemistry, like all the natural sciences, Recommanded Product: 2344-80-1, begins with the direct observation of nature¡ª in this case, of matter.2344-80-1, Name is (Chloromethyl)trimethylsilane, SMILES is C[Si](C)(CCl)C, belongs to chiral-nitrogen-ligands compound. In a document, author is Akhtar, Rabia, introduce the new discover.
Nucleophilic ring opening reactions of aziridines
Aziridine ring opening reactions have gained tremendous importance in the synthesis of nitrogen containing biologically active molecules. During recent years, a great effort has been put forward by scientists toward unique bond construction methodologies via ring opening of aziridines. In this regard, a wide range of chiral metal- and organo-catalyzed desymmetrization reactions of aziridines have been reported with carbon, sulfur, oxygen, nitrogen, halogen, and other nucleophiles. In this review, an outline of methodologies adopted by a number of scientists during 2013-2017 for aziridine ring opening reactions as well as their synthetic applications is described.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 2344-80-1. Recommanded Product: 2344-80-1.
Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis¡ªI. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
,Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis