In an article, author is Trost, Barry M., once mentioned the application of 81058-27-7, Recommanded Product: 81058-27-7, Name is (2R,3R,4S,5R,6R)-2-Bromo-6-((pivaloyloxy)methyl)tetrahydro-2H-pyran-3,4,5-triyl tris(2,2-dimethylpropanoate), molecular formula is C26H43BrO9, molecular weight is 579.5182, MDL number is MFCD08275217, category is chiral-nitrogen-ligands. Now introduce a scientific discovery about this category.
Asymmetric Electrophilic Amination and Hydrazination of Acyclic alpha-Branched Ketones for the Formation of alpha-Tertiary Amines and Hydrazines
Chiral alpha-tertiary amines can be accessed directly through the electrophilic amination of alpha-branched ketones utilizing di-tert-butyl azodicarboxylate as the electrophilic nitrogen source. This process, catalyzed by a dinuclear zinc-ProPhenol complex, proceeds under mild reaction conditions and with a diverse range of vinyl ketones. The reactions can be run on gram-scale with reduced catalyst loadings and feature a recoverable ligand. The hydrazine products are shown to undergo chemoselective N-N bond cleavage without reduction of the alpha,beta-unsaturated ketone, revealing chiral alpha-amino ketones.
If you are interested in 81058-27-7, you can contact me at any time and look forward to more communication. Recommanded Product: 81058-27-7.
Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis¡ªI. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
,Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis