The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 2-Aminoquinazolin-4(3H)-one( cas:20198-19-0 ) is researched.Synthetic Route of C8H7N3O.Masharipov, S.; Nazhimov, K. O.; Kasymova, S. S.; Askarov, M. A. published the article 《4-Quinazolone derivatives as stabilizers for PVC》 about this compound( cas:20198-19-0 ) in Plasticheskie Massy. Keywords: quinazolone derivative heat stabilizer PVC. Let’s learn more about this compound (cas:20198-19-0).
Derivatives of 4-quinazolone increased the thermal stability of PVC by 2-16 fold. The inhibiting action of 4-quinazolone derivatives during PVC degradation is due to to the binding of gaseous HCl and replacement of labile Cl atoms by the quinazolone groups, and their stabilization activity depends on the type of groups replacing H in 4-quinazolone. The thermal stability of PVC linoleum containing 2-amino-4-quinazolone-Co acetate complex was 2.5-3 fold higher than that of PVC containing com. Ca stearate, without changes in physicomech. properties and with improvement of properties in some cases.
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Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis