New explortion of (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol

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A method for the enantioselective reduction of prochiral ketones using catalytic amounts of tetrahydroindeno[1,2-d][1,3,2] oxazaboroles of formula II is disclosed. STR1 The oxazaboroles can be generated in situ from the corresponding cis-1-amino-2-indanols or imino indanols (III) STR2 Novel compounds of formulas II and III are also disclosed.

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Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis