In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Effect of various parameters on the stereoselectivity of 1,3-diene synthesis by carbopalladation of allenes, published in 1992, which mentions a compound: 3411-48-1, mainly applied to carbopalladation allene stereochem; diene stereoselective preparation; palladium pi allyl intermediate, Recommanded Product: 3411-48-1.
The effects of the temperature and of the nature of solvent, phosphine ligand and carbon nucleophile on the stereoselectivity of the palladium-catalyzed process involving 1,2-decadiene and vinyl bromide and leading to 1,3-dienes, e.g., (E)- and (Z)-CH2:CMeC(:CHR)CH2CH(CO2Et)2 (R = heptyl), have been studied. This reaction, which produces a 1:1 mixture of dienes in the conditions previously described [THF, Pd(dppe) (dppe = Ph2PCH2CH2PPh2), malonate anion] can be oriented either towards the E-isomer (75%) by using acetonitrile or a hindered phosphine or towards the Z-isomer (83%) when an anion of low nucleophilicity is involved. These results can be related to the relative stability and reactivity of both syn- and anti-π-allyl complexes which are intermediates in the process.
As far as I know, this compound(3411-48-1)Recommanded Product: 3411-48-1 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis