Electric Literature of 2344-80-1, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 2344-80-1, Name is (Chloromethyl)trimethylsilane, SMILES is C[Si](C)(CCl)C, belongs to chiral-nitrogen-ligands compound. In a article, author is Zhang, Ran, introduce new discover of the category.
Rh(II)-Catalyzed Tandem Cyclization of Aliphatic N-Sulfonyl-1,2,3-triazoles and Alcohols for the Synthesis of 6-Alkoxy Piperidin-3-ones
A diastereoselective synthesis of 6-alkoxy piperidin-3-ones based on a novel Rh(II)-catalyzed tandem cyclization of aliphatic N-sulfonyl triazoles and alcohols is reported herein for the first time, which provides a facile entry into piperidinones bearing quaternary carbons at C4 or C5 position. By employing an external chiral alcohol, the asymmetric version of the reaction has been realized.
Electric Literature of 2344-80-1, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 2344-80-1 is helpful to your research.
Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis¡ªI. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
,Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis