Related Products of 108-47-4, Chemistry involves the study of all things chemical – chemical processes, chemical compositions and chemical manipulation – in order to better understand the way in which materials are structured, how they change and how they react in certain situations. 108-47-4, Name is 2,4-Dimethylpyridine, molecular formula is C7H9N. In a article,once mentioned of 108-47-4
The synthesis, characterization, DNA interaction and antiproliferative behavior of new pi-arene ruthenium(II) piano-stool complexes with nitrogen ligands are described. Three series of organometallic compounds of formulae [RuCl2(eta6-p-cym)L] were synthesized (with L = 2-, 3- or 4-methylpyridine; L = 2,3-, 2,4-, 2,5-, 3,4-, 3,5-dimethylpyridine and L = 1,2-, 1,3- 1,4-methylaminobenzene). The crystal structures of [RuCl 2(p-cym)(4-methylpyridine)], [RuCl2(p-cym)(3,4- dimethylpyridine)] and [RuCl2(p-cym)(1,4-methylaminobenzene)] were resolved and the characterization was completed by spectroscopic UV-vis, FT-IR and 1H NMR studies. Electrochemical experiments were performed by cyclic voltammetry to estimate the redox potential of the Ru(II)/Ru(III) couple. The interaction with plasmid pBR322 DNA was studied through the examination of the electrophoretical mobility and atomic force microscopy, and interaction with ct-DNA by circular dichroism, viscosity measurements and fluorescence studies based on the DNA-ethidium bromide complex. The antiproliferative behavior of the series with L = methylpyridine was assayed against two tumor cell lines, i.e. LoVo and MiaPaca. The results revealed a moderate cytotoxicity with a higher activity for the LoVo cell line compared to the MiaPaca one.
Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. In my other articles, you can also check out more blogs about 108-47-4
Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis