Researchers are common within chemical engineering and are often tasked with creating and developing new chemical techniques, frequently combining other advanced and emerging scientific areas. Electric Literature of 126456-43-7Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. In an article, authors is , once mentioned the new application about Electric Literature of 126456-43-7.
The present invention produces novel cis-oxazolidinone compound which is racemic form or optically active form, of a formula (1) STR1 wherein R represents C1 -C6 alkyl group, C2 -C6 alkenyl group, C1 -C6 alkoxyl group, C1 -C6 alkylamino group, aryl group or halogen atom, and oxazolidinone ring is at cis-configuration, comprising reacting cis-1,2-indene epoxide of a formula (3) STR2 form, with sulfonyl isocyanate compound of a formula (4) STR3 in the presence of metal halide catalyst. Further, cis-1-amino-2-indanol is produced by hydrolyzing the oxazolidinone compound. The latter compound is useful as an intermediate of HIV-drug.
Interested yet? This just the tip of the iceberg, You can reading other blog about 126456-43-7. Electric Literature of 126456-43-7
Reference：
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis