The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: Tri(naphthalen-1-yl)phosphine, is researched, Molecular C30H21P, CAS is 3411-48-1, about The palladium-catalyzed addition of aryl- and heteroarylboronic acids to aldehydes, the main research direction is aryl substituted alc preparation; arylboronic acid aldehyde addition palladium phosphine; palladium phosphine addition reaction catalyst.SDS of cas: 3411-48-1.
Reaction of aryl- or heteroarylboronic acids with aldehydes, in the presence of PdCl2 and P(1-Nap)3, afforded carbinol derivatives in good to excellent yields. The efficiency of this reaction was demonstrated by the compatibility with nitro, cyano, acetamido, acetoxy, acetyl, carboxyl, trifluoromethyl, fluoro, and chloro groups and the possibility of involving aliphatic aldehyde or hindered substrates. Moreover, the rigorous exclusion of air/moisture is not required in these transformations.
Different reactions of this compound(Tri(naphthalen-1-yl)phosphine)SDS of cas: 3411-48-1 require different conditions, so the reaction conditions are very important.
Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis