Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Wang, Dong, once mentioned the application of 3388-04-3, Name is Trimethoxy[2-(7-oxabicyclo[4.1.0]hept-3-yl)ethyl]silane, molecular formula is C11H22O4Si, molecular weight is 246.3755, MDL number is MFCD00014485, category is chiral-nitrogen-ligands. Now introduce a scientific discovery about this category, HPLC of Formula: C11H22O4Si.
Phosphine-Catalyzed (3+2) Annulation of delta-Acetoxy Allenoates with 2-Sulfonamidomalonate: Synthesis of Highly Substituted 3-Pyrrolines and Mechanistic Insight
A mild and efficient synthetic protocol for 3-pyrrolines via the phosphine-catalyzed (3 + 2) annulation of (delta-acetoxy allenoates with 2-sulfonamidomalonate is reported. The asymmetric version (up to 83% ee) is also achieved by using phosphine (R)-SITCP as the catalyst. Mechanistic experiments disclose that the involved deprotonation of amide N-H and aza-addition to vinyl phosphonium might proceed in a concerted manner.
Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 3388-04-3, HPLC of Formula: C11H22O4Si.
Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis¡ªI. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
,Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis