In an article, author is Deng, Guozhong, once mentioned the application of 136030-00-7, Recommanded Product: (1R,2S)-1-Amino-2,3-dihydro-1H-inden-2-ol, Name is (1R,2S)-1-Amino-2,3-dihydro-1H-inden-2-ol, molecular formula is C9H11NO, molecular weight is 149.1897, MDL number is MFCD00216656, category is chiral-nitrogen-ligands. Now introduce a scientific discovery about this category.
Deracemization of Phenyl-Substituted 2-Methyl-1,2,3,4-Tetrahydroquinolines by a Recombinant Monoamine Oxidase from Pseudomonas monteilii ZMU-T01
A monoamine oxidase (MAO5) from Pseudomonas monteilii ZMU-T01 was first heterologously expressed in Escherichia coli BL21(DE3) and then used as a biocatalyst for the deracemization of racemic 2-methyl-1,2,3,4-tetrahdroquinoline derivatives to yield the unreacted R enantiomer with up to >99%ee. Sequence alignment revealed that MAO5 shared 14.7% identity toward the well-studied monoamine oxidase (MAO-N).
If you are interested in 136030-00-7, you can contact me at any time and look forward to more communication. Recommanded Product: (1R,2S)-1-Amino-2,3-dihydro-1H-inden-2-ol.
Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis¡ªI. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
,Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis