Tag: M.W=400-500

Synthetic Route of C30H21P. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: Tri(naphthalen-1-yl)phosphine, is researched, Molecular C30H21P, CAS is 3411-48-1, about A simple and practical protocol for the palladium-catalyzed cross-coupling of boronic acids with methyl iodide.

A combination of palladium acetate and tri-1-naphthylphosphine was a highly efficient catalyst system for the cross-coupling of arylboronic acids with Me iodide at room temperature The new process allows for a convenient introduction of Me groups into various functionalized arenes under mild conditions. Thus, tri-1-naphthylphosphine/palladium acetate catalyzed cross-coupling of p-nitrophenylboronic acid with Me iodide in the presence of K3PO4 in H2O/THF gave 89% 4-nitrotoluene.

The article 《A simple and practical protocol for the palladium-catalyzed cross-coupling of boronic acids with methyl iodide》 also mentions many details about this compound(3411-48-1)Synthetic Route of C30H21P, you can pay attention to it, because details determine success or failure

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: Tri(naphthalen-1-yl)phosphine, is researched, Molecular C30H21P, CAS is 3411-48-1, about The palladium-catalyzed addition of aryl- and heteroarylboronic acids to aldehydes, the main research direction is aryl substituted alc preparation; arylboronic acid aldehyde addition palladium phosphine; palladium phosphine addition reaction catalyst.SDS of cas: 3411-48-1.

Reaction of aryl- or heteroarylboronic acids with aldehydes, in the presence of PdCl2 and P(1-Nap)3, afforded carbinol derivatives in good to excellent yields. The efficiency of this reaction was demonstrated by the compatibility with nitro, cyano, acetamido, acetoxy, acetyl, carboxyl, trifluoromethyl, fluoro, and chloro groups and the possibility of involving aliphatic aldehyde or hindered substrates. Moreover, the rigorous exclusion of air/moisture is not required in these transformations.

Different reactions of this compound(Tri(naphthalen-1-yl)phosphine)SDS of cas: 3411-48-1 require different conditions, so the reaction conditions are very important.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Basicity of Very Weak Bases in 1,2-Dichloroethane, published in 2016, which mentions a compound: 3411-48-1, Name is Tri(naphthalen-1-yl)phosphine, Molecular C30H21P, Category: chiral-nitrogen-ligands.

The basicity scale of very weak bases has been set up in 1,2-dichloroethane to give, for the first time, reliable quant. insights into the basic properties of weak bases in a low-polarity solvent. The scale contains 30 compounds, including anilines; phosphanes, and carbonyl bases, such as esters and amides, linked by 53 relative basicity measurements. The scale spans more than 12 pKip units, expanding to as low pKip values as possible with our current exptl. methodol.

Different reactions of this compound(Tri(naphthalen-1-yl)phosphine)Category: chiral-nitrogen-ligands require different conditions, so the reaction conditions are very important.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

Synthetic Route of C30H21P. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: Tri(naphthalen-1-yl)phosphine, is researched, Molecular C30H21P, CAS is 3411-48-1, about Regioselective Palladium-Catalyzed Formate Reduction of N-Heterocyclic Allylic Acetates. Author is Cheng, Hsiu-Yi; Sun, Chong-Si; Hou, Duen-Ren.

The regioselective palladium-catalyzed formate reduction of allylic acetates in five- to eight-membered heterocycles is reported. Reduction of allylic acetates under mild conditions using allylpalladium chloride dimer, phosphines, and formic acid/triethylamine in DMF gave the exo-cyclic olefins in good regioselectivities and high yields. Synthetic application in preparing N-tosyl-3-oxo-piperidine is also reported.

The article 《Regioselective Palladium-Catalyzed Formate Reduction of N-Heterocyclic Allylic Acetates》 also mentions many details about this compound(3411-48-1)Synthetic Route of C30H21P, you can pay attention to it, because details determine success or failure

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

Mueller, Thomas E.; Choi, Sam Wing-Kin; Mingos, D. Michael P.; Murphy, Don; Williams, David J.; Yam, Vivian Wing-Wah published the article 《Synthesis, structural characterization and photophysical properties of ethyne-gold(I) complexes》. Keywords: crystal structure ethyne gold complex; mol structure ethyne gold complex; UV ethyne gold complex; luminescence ethyne gold complex.They researched the compound: Tri(naphthalen-1-yl)phosphine( cas:3411-48-1 ).Product Details of 3411-48-1. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:3411-48-1) here.

Closely related ethynyl-Au(I) complexes were synthesized by reaction of Au(PR3)Cl with an alk. solution of the ethyne. The mol. structures of the ethynediyl-digold complexes NpPh2PAuCCAuPNpPh2·2CHCl3 (1) (Np = naphthyl), Np2PhPAuCCAuPNp2Ph·6CHCl3 (2) and Fc2PhPAuCC-AuPFc2Ph·4EtOH (3) (Fc = ferrocenyl) and the phenylethynyl-Au complex Fc2PhPAuCC-Ph (4) were determined by single-crystal x-ray diffraction measurements. Variation of the phosphines does not have a significant influence on the bonding in the central P-Au-CC unit, the Au-P and Au-C distances being in the ranges 2.274(4)-2.289(5) and 1.983(8)-2.002(6) Å, resp. Although none of the compounds have short Au…Au contacts, compounds 1 and 2 do show novel C-H…π interactions between the proton of CHCl3 and the π-electron system of the CC bond. In 1, pairs of CHCl3 mols. are located with their protons 2.4 Å from the center of the CC bond with the C-H bond directed orthogonally towards the center of the ethyne bond. In 2, two pairs of CHCl3 mols. are located around the CC bond, with 2.5 Å between the proton and the center of the triple bond, resulting in a pseudo-octahedral arrangement around CC. In addition to the C-H…π interactions, the structures of 1 and 2 also show a range of intermol. aromatic-aromatic interactions. The 1st structural determination of naphthylphosphines resulted in estimates of their steric requirements. The UV-visible spectra of CH2Cl2 solutions of the ethynediyl compounds exhibit intense absorption bands at ∼300 nm assignable to intraligand transitions. Excitation of solid sample or fluid solution of complex 1 at λ>330 nm resulted in intense long-lived luminescence. Excitation of a solution of 2 at 350 and 380 nm led to different types of photoluminescence.

The article 《Synthesis, structural characterization and photophysical properties of ethyne-gold(I) complexes》 also mentions many details about this compound(3411-48-1)Product Details of 3411-48-1, you can pay attention to it, because details determine success or failure

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

Recommanded Product: 3411-48-1. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: Tri(naphthalen-1-yl)phosphine, is researched, Molecular C30H21P, CAS is 3411-48-1, about A Novel Triphenylphosphonium Carrier to Target Mitochondria without Uncoupling Oxidative Phosphorylation.

Mitochondrial dysfunction is an underlying pathol. in numerous diseases. Delivery of diagnostic and therapeutic cargo directly into mitochondria is a powerful approach to study and treat these diseases. The triphenylphosphonium (TPP+) moiety is the most widely used mitochondriotropic carrier. However, studies have shown that TPP+ is not inert; TPP+ conjugates uncouple mitochondrial oxidative phosphorylation. To date, all efforts toward addressing this problem have focused on modifying lipophilicity of TPP+-linker-cargo conjugates to alter mitochondrial uptake, albeit with limited success. We show that structural modifications to the TPP+ Ph rings that decrease electron d. on the phosphorus atom can abrogate uncoupling activity as compared to the parent TPP+ moiety and prevent dissipation of mitochondrial membrane potential. These alterations of the TPP+ structure do not neg. affect the delivery of cargo to mitochondria. Results here identify the 4-CF3-Ph TPP+ moiety as an inert mitochondria-targeting carrier to safely target pharmacophores and probes to mitochondria.

After consulting a lot of data, we found that this compound(3411-48-1)Recommanded Product: 3411-48-1 can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

Roselli, Christina A.; Gagne, Michel R. published an article about the compound: Tri(naphthalen-1-yl)phosphine( cas:3411-48-1,SMILESS:C1=CC2=C(C=C1)C(=CC=C2)P(C1=CC=CC2=C1C=CC=C2)C1=CC=CC2=C1C=CC=C2 ).Product Details of 3411-48-1. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:3411-48-1) through the article.

We report a computational study of the transfer of silylium from phosphine to heteroatom containing Lewis bases including ethers, phosphines and amines. The relative free energies of these compounds are compared to develop a thermodn. scale of stabilities that can help to interpret the chemoselectivity observed with complex natural products and biomass-derived sugars. Both the choice of silane and the phosphine Lewis base impact the thermodn. of this transfer.

After consulting a lot of data, we found that this compound(3411-48-1)Product Details of 3411-48-1 can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

Recommanded Product: 3411-48-1. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: Tri(naphthalen-1-yl)phosphine, is researched, Molecular C30H21P, CAS is 3411-48-1, about Steric and Electronic Effects on the Configurational Stability of Residual Chiral Phosphorus-Centered Three-Bladed Propellers: Tris-aryl Phosphanes. Author is Rizzo, Simona; Benincori, Tiziana; Bonometti, Valentina; Cirilli, Roberto; Mussini, Patrizia R.; Pierini, Marco; Pilati, Tullio; Sannicolo, Francesco.

Triarylphosphines, e.g., tris(2-R,6-X-naphthyl)phosphine (R = Me, Et, X = H, SO3H, OEt), structurally designed to exist as residual enantiomers or diastereoisomers, bearing substituents differing in size and electronic properties on the aryl rings, were synthesized and characterized. Their electronic properties were evaluated from their electrochem. oxidation potential determined by voltammetry. The configurational stability of residual phosphines, evaluated by dynamic HPLC on a chiral stationary phase or/and by dynamic 1H and 31P NMR spectroscopy, is rather modest (barriers of ∼18-20 kcal mol-1), much lower than that shown by the corresponding phosphine oxides (barriers of ∼25-29 kcal mol-1). For the 1st time, the residual antipodes of a triarylphosphine were isolated in enantiopure state and the absolute configuration assigned to them by single-crystal anomalous x-ray diffraction anal. In this case, the racemization barrier could be calculated also by CD signal decay kinetics. A detailed computational study was carried out to clarify the helix reversal mechanism. Calculations indicated that the low configurational stability of tris-aryl phosphines can be attributed to an unexpectedly easy P pyramidal inversion which, depending upon the substituents present on the blades, can occur even on the most stable of the four conformers constituting a single residual stereoisomer.

After consulting a lot of data, we found that this compound(3411-48-1)Recommanded Product: 3411-48-1 can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

HPLC of Formula: 3411-48-1. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: Tri(naphthalen-1-yl)phosphine, is researched, Molecular C30H21P, CAS is 3411-48-1, about Rhodium catalyzed hydroformylation assisted by cyclodextrins in biphasic medium: Can sulfonated naphthylphosphanes lead to active, selective and recyclable catalytic species?. Author is Elard, Maxime; Denis, Julien; Ferreira, Michel; Bricout, Herve; Landy, David; Tilloy, Sebastien; Monflier, Eric.

New sulfonated naphthylphosphanes having an average sulfonation degree around 2 were synthesized and tested as ligand in the aqueous biphasic Rh-catalyzed hydroformylation of 1-decene assisted by randomly methylated β-cyclodextrins. All these water-soluble phosphanes associated to a rhodium precursor were able to perform aqueous hydroformylation of 1-decene. The best results in terms of catalyst recovery and recycling were obtained with sulfonated 2-naphthylphosphanes. With sulfonated 1-naphthylphosphanes, formation of low-coordinated catalytic species leading to a catalyst leaching in the organic phase was postulated. These results were rationalized by considering that sulfonated 1-naphthylphosphanes are bulkier ligands than sulfonated 2-naphthylphosphanes.

After consulting a lot of data, we found that this compound(3411-48-1)HPLC of Formula: 3411-48-1 can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Carbonylation of organic halo derivatives into acids in the presence of palladium complexes, published in 1982-06-30, which mentions a compound: 3411-48-1, Name is Tri(naphthalen-1-yl)phosphine, Molecular C30H21P, SDS of cas: 3411-48-1.

The reactions of organic halides with CO to give carboxylic acids were catalyzed by the reaction products of (PhCN)2PdCl2 (I) with different ligands, e.g., phosphines, stilbines, sulfides, and quinone. Tertiary phosphines, especially Ph3P, were the most effective ligands. The activity of the halides increased in the following orders: alkyl < Ph < benzyl and Cl < Br < I. With Ph3P and I the optimal P/Pd ratio was 4-6. After consulting a lot of data, we found that this compound(3411-48-1)SDS of cas: 3411-48-1 can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis