The Absolute Best Science Experiment for (1R,2S)-1-Amino-2,3-dihydro-1H-inden-2-ol

Interested yet? Keep reading other articles of 136030-00-7, you can contact me at any time and look forward to more communication. Computed Properties of C9H11NO.

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels. 136030-00-7, Name is (1R,2S)-1-Amino-2,3-dihydro-1H-inden-2-ol, molecular formula is C9H11NO. In an article, author is Surur, Abdrrahman Shemsu,once mentioned of 136030-00-7, Computed Properties of C9H11NO.

Interconnection of sulfides and sulfoxides in medicinal chemistry

Aromatic heterocycles with basic nitrogen atoms as well as carboxylic acid derivatives are the dominating chemical space in the universe of drug-like molecules. These established and exceedingly evaluated structural motifs have to be combined with elements of diversity in order to chart less well-explored galaxies of chemical space and to be able to tackle seemingly undruggable targets. Flat scaffolds should be replaced by shapely molecular cores. In this context, it has been unheeded that phenyl rings in diaryl sulfides are less co-planar than in ethers and that the metabolic interconnection of sulfides and sulfoxides offers advantages that are unalike from the chemistry of amines and N-oxides in the CHN-O world. Moreover, sigma-hole potentials increase with the polarizability of the atom N < P < O < S and do not only play a role in long-time overlooked halogen bonds. Examples for lambda(2), lambda(4), and lambda(6) S-based functionalities related to improved solubility, reduced drug resistance, linkers in drug conjugates, drug-targeting to parasites, and as basis for drug monitoring in sports are given and discussed. Interested yet? Keep reading other articles of 136030-00-7, you can contact me at any time and look forward to more communication. Computed Properties of C9H11NO.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis¡ªI. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
,Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis