110-70-3, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. N1,N2-Dimethylethane-1,2-diamine, cas is 110-70-3,the chiral-nitrogen-ligands compound, it is a common compound, a new synthetic route is introduced below.
A single-neck RBFequipped with a magnetic stirrer was charged with methyl2-bromo-2-(4-nitrophenyl)acetate (3,7.33 g, 26.74 mmol) and EtOH (80 mL). After cooling to 0 C in an ice/waterbath. N,N?-dimethylethane-1,2-diamine (23 g, 0.26 mol) was added to the solution over 5 min. Theresulting solution was stirred at 0 C to 25 C overnight. After evaporation invacuo, the crude mixturewas purified on a silica gel column (MeOH: DCM = 10: 90) to afford compound 4 as a yellow solid (6.70 g, 100%).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of N1,N2-Dimethylethane-1,2-diamine, 110-70-3
Reference£º
Article; Young, Wendy B.; Barbosa, James; Blomgren, Peter; Bremer, Meire C.; Crawford, James J.; Dambach, Donna; Gallion, Steve; Hymowitz, Sarah G.; Kropf, Jeffrey E.; Lee, Seung H.; Liu, Lichuan; Lubach, Joseph W.; Macaluso, Jen; Maciejewski, Pat; Maurer, Brigitte; Mitchell, Scott A.; Ortwine, Daniel F.; Di Paolo, Julie; Reif, Karin; Scheerens, Heleen; Schmitt, Aaron; Sowell, C. Gregory; Wang, Xiaojing; Wong, Harvey; Xiong, Jin-Ming; Xu, Jianjun; Zhao, Zhongdong; Currie, Kevin S.; Bioorganic and Medicinal Chemistry Letters; vol. 25; 6; (2015); p. 1333 – 1337;,
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