81058-27-7, Name is (2R,3R,4S,5R,6R)-2-Bromo-6-((pivaloyloxy)methyl)tetrahydro-2H-pyran-3,4,5-triyl tris(2,2-dimethylpropanoate), molecular formula is C26H43BrO9, belongs to chiral-nitrogen-ligands compound, is a common compound. In a patnet, author is Liao, Hsuan-Hung, once mentioned the new application about 81058-27-7, Formula: C26H43BrO9.
Multiple Hydrogen-Bond Activation in Asymmetric BrOnsted Acid Catalysis
An efficient protocol for the asymmetric synthesis of chiral tetrahydroquinolines bearing multiple stereogenic centers by means of asymmetric BrOnsted acid catalysis was developed. A chiral 1,1-spirobiindane-7,7-diol (SPINOL)-based N-triflylphosphoramide (NTPA) proved to be an effective BrOnsted acid catalyst for the insitu generation of aza-ortho-quinone methides (aza-o-QMs) and their subsequent cycloaddition reaction with unactivated alkenes to provide the products with excellent diastereo- and enantioselectivities. In addition, DFT calculations provided insight into the activation mode and nature of the interactions between the N-triflylphosphoramide catalyst and the generated aza-o-QMs.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 81058-27-7. The above is the message from the blog manager. Formula: C26H43BrO9.
Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis¡ªI. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
,Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis