Related Products of 2344-80-1, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 2344-80-1, Name is (Chloromethyl)trimethylsilane, SMILES is C[Si](C)(CCl)C, belongs to chiral-nitrogen-ligands compound. In a article, author is Li, Yingjie, introduce new discover of the category.
beta-Cyclodextrin-modified covalent organic framework as chiral stationary phase for the separation of amino acids and beta-blockers by capillary electrochromatography
Covalent organic frameworks (COFs) as a novel stationary phase have attracted much attention in the field of chromatography owing to their permanent nanoscale porosity, higher surface area, and exceptional stabilities. Here, a novel isocyanate-beta-cyclodextrin-modified COF (MDI-beta-CD-modified COF) was synthesized using isocyanate-beta-cyclodextrin as the chiral selector and imine-based TpPa-1 COF as the matrix by a bottom-up strategy. The reaction condition and the structure of MDI-beta-CD-modified COF were optimized and characterized by X-ray diffraction (XRD), Fourier-transform infrared (FT-IR) spectra, nitrogen adsorption/desorption (Brunauer-Emmett-Teller [BET]), and thermogravimetric analysis (TGA). And then the coated open-tubular column (OT column) was prepared using MDI-beta-CD-modified COF as chiral stationary phase (CSP) by in situ growth approach, which exhibited excellent stability and repeatability. For seven consecutive runs, the intraday and interday relative standard deviations (RSDs) were in range from 0.35% to 2.21% for the migration time of histidine. The column-to-column reproducibility ranged from 2.39% to 3.08%. Meanwhile, the separation of eight compounds including four amino acids and four beta-blockers by capillary electrochromatography sufficiently verified the favorable chiral resolution properties of the MDI-beta-CD-modified COF-coated OT column. This strategy of fabricating MDI-beta-CD-modified COF-coated OT column expanded the application of imine-based COFs in chromatographic analytical fields.
Related Products of 2344-80-1, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 2344-80-1.
Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis¡ªI. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
,Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis