Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Product Details of 50893-53-3, 50893-53-3, Name is 1-Chloroethyl carbonochloridate, SMILES is O=C(Cl)OC(Cl)C, belongs to chiral-nitrogen-ligands compound. In a document, author is Elmas, Gamze, introduce the new discover.
Phosphorus-nitrogen compounds. Part 40. The syntheses of (4-fluorobenzyl) pendant armed cyclotetraphosphazene derivatives: Spectroscopic, crystallographic and stereogenic properties, DNA interactions and antimicrobial activities
The Cl substitution reaction of octachlorocyclotetraphosphazene, N4P4Cl8 (1), with 1.2 equimolar amounts of sodium salt of N/O donor-type bidentate ligand (2) gave four different new (4-fluorobenzyl) pendant armed cyclotetraphosphazene derivatives; namely, mono-(4-fluorobenzyl)-spiro- (spiro; 3), mono-(4-fluorobenzyl)-2-cis-4-dichloro-ansa- (2,4-ansa; 4), bis-(4-fluorobenzyl)-2-trans-6-dispiro (5) and bis-(4-fluorobenzyl)-2-trans-4-dispiro (6) cyclotetraphosphazenes of which 3 was the major product (yield 55%). Compound 3 was treated with mono and difunctional reagents to prepare the fully substituted products (3a-3j) due to its very high yield. However, tetrapyrrolidino-2-cis-4-dichloro-ansa- product (4a) was obtained from the reaction of 2,4-ansa (4) with excess pyrrolidine. The new cyclotetraphosphazenes were characterized by elemental analyses, mass spectrometry (ESI-MS), Fourier transform infrared (FTIR), H-1, C-13, and P-31 NMR techniques. The structures of 3 and 3g were determined by X-ray crystallography. 2,4-Ansa compounds (4 and 4a) have two stereogenic P atoms. The stereogenic property of 4 was identified by P-31 NMR spectra in the addition of the chiral solvating agent, (R)-(+)-2,2,2-trifluoro-1-(9′-anthryl)-ethanol (CSA). The tetraspiro compounds (3i and 3j) look similar to a propeller, and they may have P and Matropisomers. The antimicrobial activities of the compounds were screened against some G(-)/G(+) bacteria and yeast strains. The interactions of the compounds with supercoiled plasmid pBR322 DNA and their inhibited DNA restriction were examined. (C) 2018 Elsevier B.V. All rights reserved.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 50893-53-3. Product Details of 50893-53-3.
Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis¡ªI. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
,Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis