Category: chiral-nitrogen-ligands. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 5-(4-Pyridyl)-1H-tetrazole, is researched, Molecular C6H5N5, CAS is 14389-12-9, about Expanded perlite: an inexpensive natural efficient heterogeneous catalyst for the green and highly accelerated solvent-free synthesis of 5-substituted-1H-tetrazoles using [bmim]N3 and nitriles. Author is Jahanshahi, Roya; Akhlaghinia, Batool.
A versatile, green and highly accelerated protocol for preparing 5-substituted-1H-tetrazoles was reported. In this method, 5-substituted-1H-tetrazoles were synthesized from nitriles and [bmim]N3, in the presence of the expanded perlite as an inexpensive natural efficient heterogeneous catalyst, under solvent-free condition. A wide variety of aryl nitriles underwent [3+2] cycloaddition to afford the desired tetrazoles in good to excellent yields, rapidly. This method had the advantages of high yields, short reaction times, simple methodol. and easy work-up. The catalyst was recovered by simple filtration and reused delivering good yields.
The article 《Expanded perlite: an inexpensive natural efficient heterogeneous catalyst for the green and highly accelerated solvent-free synthesis of 5-substituted-1H-tetrazoles using [bmim]N3 and nitriles》 also mentions many details about this compound(14389-12-9)Category: chiral-nitrogen-ligands, you can pay attention to it, because details determine success or failure
Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis